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Prof. Andrew Scott AM

HEAD, TUMOUR TARGETING LABORATORY | SCIENTIFIC DIRECTOR OF POSITRON EMISSION TOMOGRAPHY, DEPARTMENT OF MEDICAL IMAGING AND THERAPY, AUSTIN HEALTH

More about Prof. Andrew Scott AM

Throughout my research career as a translational clinician-scientist I have had an abiding interest in the mechanisms of tumour cell growth, and the development of innovative strategies to improve diagnosis and therapy for cancer patients.

The areas of my major research focus have been in the definition and characterisation of antigen and receptor targets for cancer therapy; signaling and metabolic pathways in cancer cells; antibody-based therapy and immune regulation of tumours, and molecular imaging of cancer.

I have developed a program to translate our laboratory discoveries into the clinic which has led to 10 novel antibodies and recombinant proteins progressing successfully through first-in-human, Phase I and II cancer trials. This program has delivered key outcomes including 15 patents and the licensing of seven discoveries to Pharma and Biotech.

I have published over 260 peer reviewed papers and 20 book chapters, principally in the areas of oncology and molecular imaging. Invited reviews in leading journals include Nature Reviews Cancer and Cancer Research.

I am actively involved in the training and mentoring of young scientists and clinicians and currently supervise several doctoral students in addition to post-doctoral fellows and Nuclear Medicine trainees.

Further to my research and clinical activities, as President of the World Federation of Nuclear Medicine and Biology, the peak global Nuclear Medicine organisation, I am engaged in strategic planning for training, health care policy, and advocacy for molecular imaging and nuclear medicine therapy within the US, European, South American, Asia-Oceania, and African regions, and with the IAEA and WHO.

National leadership includes being a foundation Board member of Cancer Trials Australia, and a Board member of the Victorian Cancer Biobank, which have successfully implemented tumour tissue banking protocols across Victoria, and also created a world-class multi-site cancer clinical trials network that now extends across Victoria and into NSW.

I am also a Board member of the Australian Nuclear Science and Technology Organisation (ANSTO), and participate in policy and governance activities for this Australian Government organisation.

Education

FAANMS, Fellowship Australasian Association of Nuclear Medicine Specialists

FAICD, Fellow of Australian Institute of Company Directors

MD, Doctor of Medicine, University of Sydney, Australia

DDU, Australasian Society for Ultrasound in Medicine

FRACP, Fellowship Royal Australasian College of Physicians

ECFMG, Certified for US practice

MB BS (Hons), Bachelor of Medicine and Bachelor of Surgery (with Honours), University of Sydney, Australia

Fellowships: Memorial Sloan-Kettering Cancer Center

Current Appointments

Head Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute

Member, Ludwig Institute for Cancer Research

Scientific Director of Positron Emission Tomography, Department of Medical Imaging and Therapeutics, Austin Health, Melbourne

Professor, School of Cancer Medicine, LaTrobe University

Professor, Department of Medicine, University of Melbourne

Professor, Department of Biochemistry, Monash University

Achievements

Order of Australia Award (AM) For significant service to nuclear medicine and cancer research as an academic, and to professional organisations.

Distinguished Scientist Award, Austin Medical Research Foundation 2014

Inaugural Pioneer Award, Australian and New Zealand Society of Nuclear Medicine

Journal of Nuclear Medicine Editors Choice Award for best clinical manuscript, 2008

Medical Board Traveling Fellowship, Royal North Shore Hospital, Sydney, Australia

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