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Lokman

Lokman Pang

PhD Student

More about Lokman Pang

I love how science presents endless possibilities and new challenges every day. I am grateful to be working with a group of remarkable scientists towards improving the health and outcomes of patients.

My interest in cytokine signalling was ignited during my time at the University of Melbourne studying for my undergraduate degree. I undertook my honours degree at St Vincent’s Institute in partnership with the University of Melbourne, whereby I investigated the role of STAT3 in the pancreas during diet-induced diabetes. Following completion of my degree, I worked as a Research Assistant for an additional year, where I aimed to finish my previous work as well as expand my research skills with A/Prof Carl Walkley.

In 2018, my curiosity for cytokine signalling has drawn me to the ONJCRI, where I am currently pursuing my PhD under the supervision of Dr. Ashwini Chand and Prof. Matthias Ernst. My PhD project aims to determine if the Signal Transducer and Activator of Transcription 3 (STAT3) has a role in modifying intestinal barrier function and the gut microbiome. As colorectal cancer remains one of the most common fatal malignancies worldwide, I hope that my project's findings may be exploited therapeutically in order to modulate intestinal barrier function, thereby improving patient response to immunotherapy and chemotherapy. 

Education

2016 Bachelor of Science with Honours, The University of Melbourne 

Achievements

Current recipient of La Trobe University Postgraduate Research Scholarship and La Trobe University Full-Fee Research Scholarship

2016 SVI Foundation Top-up Scholarship Award

Recent Publications

Sara A. Litwak, Lokman Pang, Sandra Galic, William J. Stanley, Jean-Valery Turatsinze, Kim Loh, Daniel J. Gough, Decio L. Eizirik, Esteban N. Gurzov. JNK activation of BIM promotes hepatic oxidative stress, steatosis and insulin resistance in obesity. Diabetes (2017)

Jacki E Heraud-Farlow, Alistair M Chalk, Sandra E Linder, Qin Li, Scott Taylor, Joshua M White, Lokman Pang, Brian J Liddicoat, Ankita Gupte, Jin Billy Li, Carl R Walkley. Protein recoding by ADAR1-mediated RNA editing is not essential for normal development and homeostasis. Genome Biology (2017)

Xinwei Ge, Aleksandr Kakinen, Esteban N. Gurzov, Wen Yang, Lokman Pang, Emily H. Pilkington, Praveen Govindan-Nedumpully, Pengyu Chen, Frances Separovic, Thomas P. Davis, Pu Chun Ke, Feng Ding. Zinc-coordination and C-peptide complexation: a potential mechanism for the endogenous inhibition of IAPP aggregation. Chemical Communications (2017)

 

Email: lokman.pang@onjcri.org.au

 

 

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